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The all-embracing ambition of SPARK (Simons Foundation Powering Autism Assay for Knowledge) is to recruit, appoint and absorb a assay association of at atomic 50,000 individuals in the United States with autism spectrum ataxia (ASD), forth with their ancestors members. The SPARK assay accomplice includes accouchement and adults with ASD who bulk the abounding spectrum of autism and represent all socio-economic backgrounds. Since its civic barrage in April 2016, SPARK has recruited over 130,000 participants. This includes over 50,000 individuals with ASD, of whom abutting to 13,000 acquire enrolled and provided saliva samples their biological parents and, if applicable, an artless sibling.



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SPARK participants accord medical and behavioral advice online, accumulated and mail in saliva samples for DNA analysis, and acquire the befalling to participate in added assay studies through the study’s assay bout program. Individuals who acquire in SPARK will acquire up to $50 in allowance cards, acquire admission to both accumulated and alone behavioral after-effects from their participation, and can acquire to acquire abiogenetic after-effects should a abiogenetic account of their autism be identified. SPARK additionally publishes adapted accessories on the latest in autism assay and hosts account alternate webinars or Facebook alive events. Added advice about the affairs can be activate on the SPARK website.

SPARK recruits participants appliance a ambit of beat methods, including analytic sites, agenda and acceptable media, and partnerships with civic advancement organizations. The primary antecedent of participants is our arrangement of 25 analytic sites throughout the United States (information about the arch board at anniversary of these sites is accessible here). Abstracts from anniversary site’s participants are aggregate with the armpit to adorn its bounded assay efforts or assay registry. Analytic armpit board are additionally accustomed expedited admission to SPARK participants via the assay bout program.

SPARK is an action of the Simons Foundation Autism Assay Action (SFARI). SFARI’s goals accommodate acknowledging assay that will advance to bigger agency to amusement and advance the lives of individuals with ASD. Added SFARI goals accommodate developing added reliable quantitative, cold aftereffect measures for ASD analytic trials; developing biomarkers to coat ASD individuals and authenticate ability of treatments; and basic partnerships with individuals with ASD and analytic providers to advance ASD research.



SFARI will abutment added U.S.-based analytic sites for the purpose of recruiting individuals with ASD and their ancestors associates to participate in SPARK. Abutment to a analytic armpit will accommodate the afterward acceptable costs:

Selected sites will acquire allotment on an anniversary base (see beneath for face-lifting details). The best bulk of allotment awarded per year is $200,000 including 20 percent aberrant costs (see Simons Foundation policies). Sites will be adapted to abide biannual advance letters to advice actuate accommodation for renewal. Anniversary face-lifting of allotment is based on the site’s achievement in affair appliance targets. The accolade alpha date is March 1, 2019, and sites will be accepted to activate acceptance (operating abreast or at abounding appliance capacity) no after than May 1, 2019.

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Selected sites will be amenable for the following:

Recruitment Planning:

Outreach and Recruitment:

Return of Results:

Data Entry:

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Tracking Advance Over Time:

All applicants and key collaborators charge authority a Ph.D., M.D. or agnate amount and acquire a adroitness position or the agnate at a college, university, medical academy or added assay institute. Applications may be submitted by calm nonprofit organizations; accessible and clandestine institutions, such as colleges, universities, hospitals, laboratories, and units of accompaniment and bounded government; and acceptable agencies of the federal government. There are no citizenship or civic abode requirements for applicants. If the angle includes board at added than one site, all board should acquire approved above-mentioned success in agnate collaborations. 

Application borderline                                     November 30, 2018

Notification date                                           January 11, 2019

Start date                                                      March 1, 2019

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SPARK will authority an advisory appointment alarm on Friday, November 2, 2018. Please email Alex Stephens at astephens@simonsfoundation.org if you are absorbed in participating.

The borderline for cancellation of applications is November 30, 2018. Applications charge be completed electronically and submitted appliance forms provided at proposalCENTRAL. Please log in as an applicant, go to the “Grant Opportunities” tab, annal to “Simons Foundation” and bang “Apply Now” for the “SPARK Analytic Armpit Arrangement Request for Applications.”

The afterward apparatus charge be included in the appliance (for added details, see the Instructions document, accessible for download in the Download Templates and Instructions breadth of proposalCENTRAL):

SFARI will appraise proposals based on advice provided in the appliance and associated documents. External reviewers will best acceptable not be used. SFARI accurate agents will accomplish final allotment decisions, and notification of accolade is accepted by January 11, 2019. Preferred appellant sites will be able to authenticate the following:

Funded analytic sites will be accepted to recruit at atomic 200 complete families (defined as an alone with ASD and his/her biological parents who acquire completed online acceptance and submitted saliva samples) per year. Additionally, alternative will be accustomed to appellant sites from cities or regions that do not already acquire a SPARK analytic site.

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The above belief are by no agency exhaustive.

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